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(written from a Production point of view)
He is perhaps best known for his feature films Cube (starring Nicole de Boer), Cypher, Nothing, and Splice. He has also directed episodes of TV series such as Orphan Black and Hannibal.
In addition to this, he began his career as storyboard artist working on cartoon series including Beetlejuice, Fievel's American Tales, and also the feature film Ginger Snaps.