One of her three husbands, Groznik, did something horrible to upset her prior to 2149. When Feezal came aboard Enterprise NX-01 in 2152, one of the questions Phlox asked her was if "Vesna had forgiven Groznik yet". She hadn't, as he had apologized "only" twice. Feezal believed Vesna wouldn't forgive Groznik for another two years. (ENT: "Stigma")
This character was only mentioned in dialogue.
The name of this character was spelled "Vesna" in the final draft script of "Stigma".  It is also pronounced that way on screen, by Phlox actor John Billingsley. However, the name is misspelled "Vesena" in the episode's closed captioning.