This class of vessel, manned by a crew of fifteen or twenty Hirogen hunters, was considerably larger than both the standard Hirogen warship and the Starfleet Intrepid-class starship. The design also had a major flaw in its sensor system whereby its engines created a "blind spot" in the ship's aft section, in which smaller ships could hide and avoid sensor detection.
In 2377, the USS Voyager exploited the blind spot weakness to secretly follow two Venatic-class ships that were pursuing a third ship crewed by Hirogen prey holograms into a nebula. They were later disabled by Voyager. (VOY: "Flesh and Blood")