The Unefra system was a star system in Cardassian space near the Cardassian-Romulan border.

Enabran Tain maintained a safe house on Unefra III. Elim Garak and Odo came to the Unefra system in 2371 aboard the runabout USS Mekong to search for him. There, they were captured by Tain's Romulan warbird. (DS9: "Improbable Cause")

The Unefra system is probably located in the Algira sector.
According to the Star Trek: Star Charts, on page 46, the Unefra system's primary was a Class F star. It had a magnitude of +7, which was 1/10 as bright as Sol. This system was located in the Alpha Quadrant.

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