The USS Noble was a 24th century Federation starship operated by Starfleet.

In 2370, after the USS Hera was reported missing, the USS Excelsior and the Noble retraced the Hera's course for six days. The search failed at finding any evidence of the lost starship. (TNG: "Interface")

The script for the scene where the Noble was mentioned gave the spelling used on this page. However, the Star Trek Encyclopedia mentioned this vessel as being one and the same as the USS Nobel, which was featured on a large computer display in some DS9 episodes.