The USS Madison was a Federation starship in service during the 24th century.
In 2373, the Madison was part of the fleet commanded by Admiral Hayes that first intercepted the Borg cube in the Typhon sector and then followed the Cube to Earth, where it could finally be destroyed in the Battle of Sector 001. (Star Trek: First Contact)
A Commander amed Ludwig served aboard the Madison during this battle.
- The name Madison was overheard among the radio chatter at the beginning of the battle. Nothing else is known about the ship.