The USS K'Marco was a 24th century Federation starship operated by Starfleet.

In 2369, the K'Marco was named on the chart "Sector Ipai Relay Log – Relay Message Flow 1293" in Relay Station 47 Ops. This ship, in Sector 5501, sent a message on Starfleet Commnet One via Gamma One-Three. The ship's next mission was warp drive performance tests. (TNG: "Aquiel" production art)

This starship was only mentioned in writing.