The USS Ganges (NCC-72454) was a 24th century Federation Danube-class runabout operated by Starfleet. The ship was assigned to Deep Space 9.

In 2369, the Ganges was one of three runabouts delivered to the new starbase Deep Space 9 by the starship USS Enterprise-D. (DS9: "Emissary")

The Ganges was outfitted with a rollbar containing sensor equipment when it assisted in the apprehension of Bajoran terrorist Tahna Los a few weeks later. (DS9: "Past Prologue")

On a routine mission into the Gamma Quadrant, the Ganges picked up Human archaeologist Vash, who had been in the Gamma Quadrant for two years. On the way back to the station, the Ganges suffered a mysterious loss of power. (DS9: "Q-Less")

Odo used the Ganges to ferry the fugitive Croden back to the Gamma Quadrant. Instead of returning Croden to the Rakhar homeworld, Odo went to the Chamra Vortex, where Croden retrieved his daughter, Yareth, in stasis. The Ganges was fired upon by Ah-Kel in his Theta-class Miradorn raider in the nebula before escaping and beaming Croden and Yareth to the Vulcan ship T'Vran. (DS9: "Vortex")

Jadzia Dax and Kira Nerys took the Ganges to scan the moon Jerrado for lifeforms and found Mullibok, Baltrim, and Keena in their cottage. When Mullibok refused to leave and invited Kira for supper, she contacted Dax aboard the Ganges and told her that she could head back to the station. (DS9: "Progress")

In 2370, the Ganges was the last runabout to evacuate DS9 in the face of the short-lived Bajoran coup. (DS9: "The Siege")

The Ganges was destroyed by a T'Lani cruiser later that year. (DS9: "Armageddon Game")

The Ganges was "named after the river in northern India and eastern Pakistan that flows 1560 miles from the Himalayas to the Bay of Bengal." (Star Trek Encyclopedia (4th ed., vol. 1, p. 296)) The Encyclopedia assigned the registry number NCC-72454 to the Ganges, with the number seen on a starboard profile view of this runabout. This registry was confirmed in the canon where it was visible on wreckage of the Ganges, sold in the It's A Wrap! sale and auction. [1]

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