The USGS Powell was a 24th century starship registered for Federation travel. In 2370, the captain of this ship was S. Sondheim. The starship's point of departure was Hispaniola Minor. The starship arrived at Deep Space 9 on stardate 47550.5. The USGS Powell was listed on the space station's arrival roster. (DS9: "Whispers", production art)

This starship was only mentioned in writing.
The starship was presumably named after John Wesley Powell, who served as the second director of the United States Geological Survey (USGS) from 1881 to 1894.