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Notable scientists at the Ministry included Lenara Kahn, Hanor Pren, and Bejal Otner, all of whom visited Deep Space 9 in 2372 to conduct experiments in the creation of artificial wormholes. (DS9: "Rejoined")
The Ministry later found a way to collapse the Alpha Quadrant terminus of the Bajoran wormhole, without harming the Prophets. This attempt was sabotaged by a Changeling, posing as Julian Bashir. (DS9: "In Purgatory's Shadow")