Tobacco was a highly addictive and poisonous substance smoked on Earth until at least the 21st century.
During the 19th century tobacco was on sale in a shop in the Irish village of Fair Haven, if the holoprogram Paris 042 is to be believed. (VOY: "Fair Haven")
When Data first learns of Sherlock Holmes, he is smoking a pipe at least once, demonstrating that tobacco is still used in limited form.
When Quark, Rom and Nog found themselves in 1940s Earth, virtually all of the Humans they encountered were smokers. Quark had a particularly negative reaction to the tobacco smoke. (DS9: "Little Green Men")