The thyroid was a large gland found in a humanoid's endocrine system, which regulated hormones in the body.

In Takarans, the thyroid gland was located in the lateral sternal. (TNG: "Suspicions")

In 2267, to snap Spock out of his Omicron spore-induced spell, James T. Kirk taunted him by calling him, among other things, "an elf with a hyperactive thyroid" (TOS: "This Side of Paradise")

In 2371, Doctor Julian Bashir found no thyroid problems while examining a Jem'Hadar baby Quark had unknowingly taken possession of. (DS9: "The Abandoned")

In the Denobulan language, the phrase for the thyroid gland is "Ya-sah mai gaa-am". Phlox mentioned this while testing Hoshi Sato's Denobulan while she was recovering after being injured by a Romulan mine in 2152. (deleted scene, ENT: "Minefield")

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