The thoracic cavity or chest cavity was the chamber of the body protected by the thoracic wall.

In 2366, the Zalkonian later nicknamed "John Doe" was discovered with major trauma to his chest cavity, but made a full recovery. (TNG: "Transfigurations")

In 2370, Quark's thoracic cavity was ruptured by a compressed tetryon beam fired by Trazko. (DS9: "Necessary Evil")

In 2371, Fred Noonan suffered severe trauma to his thoracic cavity, caused by weapons fire. (VOY: "The 37's")

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