The Temecklian virus was a contagious disease known to have outbreaks on Bajor.

In 2372, Constable Odo used an outbreak of Temecklian virus on Bajor as an excuse to conduct a class 2 inspection of Kasidy Yates' freighter, the Xhosa, when she was suspected of being a Maquis smuggler. Yates protested, saying that none of her cargo came from Bajor, and she and convinced Captain Sisko to let her leave without the inspection by promising to flood her entire cargo hold with baryon radiation as a precaution. (DS9: "For the Cause")

According to Star Trek: Star Charts ("United Federation of Planets III") and Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), there was a star system named Temecklia, which might possibly be the system of origin for this virus, in the Alpha Quadrant. The primary of this system was a K-class star. In the late 24th century, it was an independent system.