Sybaron was a location in space, where the Seventh Fleet took heavy losses there in 2374, during the Dominion War. (DS9: "The Reckoning")

This location was only mentioned in dialogue.
The encounter at Sybaron was mentioned in the novel Hollow Men. In the novel it was identified as a star system.
According to Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), Sybaron was the name of a star system in the Alpha Quadrant. The system's primary was a M-class star.

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