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Susan Khouri was a 22nd century Human female medical technician and member of the xenophobic movement known as Terra Prime.

By 2154, Khouri had joined the Terra Prime movement and left Earth to work for them in the Orpheus Mining colony. To deal with the low-gravity environment, she had to take injections of myofibrilin. In 2155, Khouri acted as caretaker of the baby girl who was created as a binary clone of Commanders Charles Tucker and T'Pol. John Frederick Paxton, Terra Prime's leader, intended to use the child as a rallying point for his anti-alien views and then destroy her. Khouri, however, had become very attached to the child, and decided to warn Tucker and T'Pol of Paxton's plot. She was shot and critically wounded by a phase-pistol while traveling to San Francisco. She managed to barely reach T'Pol, giving her a hair sample from the baby and only barely explain when she succumbed to her wounds. (ENT: "Demons")

Khouri was played by Christine Romeo.
In the final draft script of "Demons", Khouri was described thus; "She's in her 30's, pale, her forehead beaded with sweat. She's fighting excrutiating pain."