Supreme Directive 2645 was the official order given by the Cardassian Union to free all Bajorans from Cardassian prisons.

The directive was not followed in full, as at least a dozen Bajorans including Li Nalas were kept at the Hutet labor camp on Cardassia IV as late as 2370. Gul Dukat assured Benjamin Sisko and Kira Nerys that Central Command had no knowledge of this and the camp's prefect would be punished for violating Supreme Directive 2645. (DS9: "The Homecoming")

Despite this incident, the directive apparently continued to be violated as the Cardassians released several more prisoners in "Profit and Loss".

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