Supply and Maintenance was a department located aboard Constitution-class starships of the mid-23rd century. This department was responsible for the supplying and maintaining of equipment for the ship's crew.

In 2266, Lieutenant Nyota Uhura, a communications officer aboard the USS Enterprise, was running through file photos of crew members to identify a strange crewman who had approached her in a corridor. The lieutenant found no matches to the crewman she had seen with crewmen assigned to this department. Under instruction from Lieutenant Hikaru Sulu, she proceeded to run through photos of crewmen assigned to the engineering deck. (TOS: "The Man Trap")