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This page contains information regarding new Star Trek material, and thus may contain spoilers.

Starbase 343 was a Federation starbase administered by Starfleet.

The starbase was operational by at least 2256. (DIS: "Choose Your Pain")

In 2366, the USS Enterprise-D was diverted to the starbase to transport urgently needed medical supplies to the Alpha Leonis system, postponing its rendezvous with the USS Goddard. Several Enterprise crewmembers took extended shore leave here during this transport, as it was expected to be a quiet mission. (TNG: "The Vengeance Factor")

According to the Star Trek: Star Charts (p. 64) and the Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), Starbase 343 was located in the Beta Quadrant.

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