Starbase 157 is a Federation outpost administrated by Starfleet.
In 2366, this base picked up the final distress call from the transport Lalo. The Lalo reported encountering an unknown, cube-shaped vessel, which was later encountered and identified by the Enterprise-D as a Borg ship. (TNG:"The Best of Both Worlds, Part I")
- This base was mentioned in the dialogue of Admiral Hanson's briefing.