Starbase 123 was a Federation starbase administered by Starfleet.

In 2366 Starbase 123 detected two Romulan D'deridex-class cruisers on an intercept course with Tin Man, just prior to Starfleet's contact with that lifeform. (TNG: "Tin Man")

This starbase was only mentioned in dialogue.
According to Star Trek: Star Charts (p. 63) and Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), Starbase 123 was located in the Beta Quadrant.
This starbase was also referenced in the Pocket TNG novel Boogeymen.

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