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A sprain was a term used to describe the tearing of one or more ligaments surrounding a joint.
In 2152, Dr. Phlox informed Captain Jonathan Archer that a few bruises and sprains were suffered when some of the Enterprise NX-01 crew lost consciousness as a result of unusual radiation from a trinary star system. (ENT: "Singularity")
In 2371, Kathryn Janeway ordered Harry Kim to stand at ease before he sprained something, after the ensign stood too rigidly to attention upon meeting his captain for the first time. (VOY: "Caretaker")