(written from a Production point of view)
In the script for the Star Trek: The Next Generation episode "Violations", Sector 22139 was a sector. The Federation starship USS Enterprise-D was on a mapping survey of this sector. It was transporting a delegation of Ullian telepathic historians to Kaldra IV. The most unusual thing seen by the crew was a binary system.
The name of this sector was not mentioned in the episode.