It was about twenty square blocks large, and contained an estimated ten thousand people living in very bad and overcrowded conditions. It was walled off from the rest of the city, its major access point being the "main gate." It was active at least in 2022.
Among its amenities were a processing center for new arrivals, a clinic, and distribution points for food and water. The distribution points were known to have lines. The administration also offered a job placing service, although according to the residents it was not effective. The district was policed by a specialized police force, known as Sanctuary District Police or District Security.
One street in the district was called Second Street. It also contained a red and a blue zone, each with their own requirements.
The abbreviation "SFSD" could be seen one some documents of the district administration in a context suggesting an abbreviation for the San Francisco Sanctuary District.
Ten thousand people was the generally accepted population(citation needed • edit), but Sisko suggested that the population was slightly less, around 9,500. Of course these figures should not be taken literally, as both were made clear to be estimates.