The Sampalo relic was an archaeological artifact from Hoek IV in the Lantar Nebula. In 2369, Q tried to tempt Vash into rejoining him as a partner by offering to show her the Sampalo relic. (DS9: "Q-Less")

According to Star Trek: Star Charts (p. 74), there was a star system named Sampalo, in which this relic might possibly have originated, in the Gamma Quadrant. This was a binary star system with a M-class star and a G-class star.