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While stationed on Denobula during mating season, doctor Jeremy Lucas wrote that while he used to think Human reproduction was complicated, but Denobulans make them look like single-cell organisms. (ENT: "Cold Station 12")
While on an away mission on Gamma Trianguli VI, Pavel Chekov and Martha Landon discussed their desire to be alone together in a place described as the Garden of Eden, Captain James T. Kirk, who overheard their flirtations, interjected, stating "I know you find each other fascinating, but we're not here to conduct a field experiment in Human biology." Later, when the Feeders of Vaal witnessed the affection between Chekov and Landon, they described the need for "replacements" to be unnecessary, and such acts to be "forbidden by Vaal." (TOS: "The Apple")
In 2267, James T. Kirk tried discussing Vulcan reproduction with Spock by saying that it happened to the birds and the bees. Spock countered that Vulcan reproduction was nothing like that and went on to describe Pon farr, the Vulcan way of mating. (TOS: "Amok Time")
While trying to find out if a certain phenomena constituted a life form despite being inorganic, doctor Beverly Crusher suggested that growth and development, aka reproduction, might be a good basis for for any definition of life organic or inorganic. (TNG: "Home Soil")