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The kidney is an excretory organ. It functions to maintain the water, the acid-base concentration, and filter the blood; the waste products are excreted as urine. The organ is described by the Malcorians and Gosis' species as the renal organ.

Denobulan lemur kidneys were a delicacy (ENT: "A Night in Sickbay"), as was kidney pie on Earth. (TNG: "The Wounded")

In 1986, Dr. Leonard McCoy gave a kidney pill to an elderly woman in San Francisco who was suffering from "kidney dialysis." The pill apparently caused the spontaneous growth of a new kidney. (Star Trek IV: The Voyage Home)

In 2153, Major Hayes was left with a bruised kidney following a fight with Malcolm Reed. (ENT: "Harbinger")

In 2268, McCoy suffered 70% kidney failure after being tortured by the Vians. (TOS: "The Empath")

In 2269, McCoy told Janice Lester, who had taken over James Kirk's body, that his kidneys were "functioning at their usual, normal peak of efficiency." (TOS: "Turnabout Intruder")

After living with Spock's katra in his head, McCoy stated that he would have "felt safer giving him one of his kidneys than having what was scrambled in his brain." (Star Trek III: The Search for Spock)

Kidneys were featured in a joke Data told Geordi La Forge in early 2364. (TNG: "Code of Honor")

In 2372, a duplicate of Tuvok created by a subspace divergence field was attacked and killed by the Vidiians. Tuvok's right kidney was damaged when he was fired upon. (VOY: "Deadlock")

In 2375, Samantha Wildman suffered a punctured kidney following the crash of the Delta Flyer. (VOY: "Once Upon a Time")

Soon after, B'Elanna Torres' kidneys began to fail when she was attacked by a cytoplasmic lifeform. (VOY: "Nothing Human")

There is a widely circulated tale amongst Starfleet cadets about a man who got invited to an evening of passion with a woman on Risa, only to wake up with a missing kidney. (VOY: "Fury")

In 2377, Chakotay was knocked unconscious by a chronokinetic surge and taken to sickbay. Upon examination, The Doctor found his body was in a state of temporal flux, as he had the liver of an eighty-year old and the kidneys of a twelve-year old boy. Fortunately, The Doctor injected Chakotay with a chroniton-infused serum which brought his body back into temporal alignment. (VOY: "Shattered")

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