Regeneration was a process of repair or renewal. Regenerating damaged tissue was an important field in medicine. In addition, regeneration was a natural activity undertaken by some species during their resting cycle, analogous to sleep.
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A Borg drone can function for up to 200 hours before needing to regenerate. Seven of Nine, once she was separated from the Collective, needed to regenerate for at least three hours a day to maintain her health. (VOY: "Hunters")
Borg drones also regenerate outside of their alcoves when nanoprobes repair the drone itself, with their cybernetic components being undergoing maintenance and repair on a microscopic level, as they could also repair cells. (ENT: "Regeneration")
The effect of the Borg cube's regeneration in "Q Who" was created by building a scale replica of a Borg cube's 'wall', melting it with a blowtorch, and then playing the footage in reverse during filming.(citation needed • edit)