Regeneration was a process of repair or renewal. Regenerating damaged tissue was an important field in medicine. In addition, regeneration was a natural activity undertaken by some species during their resting cycle, analogous to sleep.
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Borg drones also regenerate outside of their alcoves when nanoprobes repair the drone itself, with their cybernetic components being undergoing maintenance and repair on a microscopic level, as they could also repair cells. (ENT: "Regeneration")
The effect of the Borg cube's regeneration in "Q Who" was created by building a scale replica of a Borg cube's 'wall', melting it with a blowtorch, and then playing the footage in reverse during filming. (citation needed • edit)