(written from a Production point of view)
A theater graduate from Otterbain College, Harris made her television debut in a 1993 episode of the science fiction series seaQuest DSV. After her appearance on Voyager in 1997, she had a recurring role on the series Sister, Sister and went on to appear on Judging Amy, Friends, Curb Your Enthusiasm, The West Wing, 8 Simple Rules, Monk, and The Sarah Silverman Program, among others. She also served as a correspondent on The Daily Show with Jon Stewart from 2002 through 2003. Since 2003, she been making recurring appearances on the Comedy Central series Reno 911!, playing Debbie Dangle, the ex-wife of Lt. Jim Dangle (Thomas Lennon).
She also had a role in the 2001 film The Gristle, starring Michael Dorn, and the 2002 action-comedy Showtime, which featured a cameo by William Shatner. She can also be seen in the Christopher Guest "mockumentaries" Best in Show (2000), A Mighty Wind (2003), and For Your Consideration (2006). All three of these films also featured Ed Begley, Jr. and Michael McKean. Harris' other film credits include Daddy Day Care (2003, with Jimmy Bennett and Wallace Langham), The Haunted Mansion (2003, with Wallace Shawn, Derek Mears, and Michael McAdam), Starsky & Hutch (2004, with David Soul and Fred Williamson), After the Sunset (2004, with Robert Curtis Brown and Mark Moses), and Kicking & Screaming (2005, with Matt Winston). In 2009, she was seen in the drama The Soloist and in the blockbuster comedy The Hangover.
More recently, Harris co-stars as psychiatrist and love interest of the title character, Linda Martin, in the FOX fantasy/crime series Lucifer (2015-2017) for which Scott Chambliss worked as production designer on the pilot episode.