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A quadruped is a four-legged animal.

In his "Ode to Spot," Data noted that Spot was an "endothermic quadruped, carnivorous by nature." (TNG: "Schisms")

The Lan'Tuana sector is inhabited by quadrupeds. (VOY: "Bliss")

Doctor Phlox professed to Jonathan Archer that he had underestimated Archer's attachment to his "subservient quadruped". (ENT: "A Night in Sickbay")

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