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Prema II was a Delta Quadrant planet that contained a Talaxian mining colony.
In 2372, the colonists agreed to help the USS Voyager in the event of a Kazon attack. (VOY: "Basics, Part I")
After Voyager was captured by the Kazon-Nistrim, two Talaxian ships from Prema II assisted in Tom Paris' plan to retake the ship. (VOY: "Basics, Part II")