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Plasti-skin was a topical anesthetic used for treating burns.

In the mid-2270s, as the USS Enterprise was struck by a plasma energy bolt fired from V'ger, Lieutenant Chekov suffered burns to his right wrist and hand when his weapons console overloaded. Using a spray applicator, Doctor Christine Chapel sprayed plasti-skin onto his wounds. (Star Trek: The Motion Picture)

The name for this medication was from the shooting script.

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