Miss Piper was a female Human Starfleet enlisted crewmember in the 23rd century. She served in the operations division of Starbase 11 in 2267, under the command of Commodore José I. Mendez. Piper was Mendez's assistant.
That same year, Piper greeted a landing party from the USS Enterprise, including Captain Kirk, and assured them that, despite Mr. Spock having asserted that they had received a message diverting them to the starbase, the base had sent no such message. Piper subsequently informed Kirk that they had a mutual acquaintance in Starfleet officer Lieutenant Helen Johansson, although she was evasive as to how much detail Johansson had gone into, regarding Kirk.
Later, Piper was monitoring Fleet Captain Christopher Pike on a computer screen, and immediately noticed when he disappeared, having been abducted by Spock, who was attempting to illegally transport Pike to planet Talos IV. (TOS: "The Menagerie, Part I")