The pineal gland was a small endocrine gland in the vertebrate brain.

Phlox once had a patient suffering from the Kamaraazite flu, who sneezed so hard he nearly regurgitated his pineal gland. (ENT: "Sleeping Dogs")

Nygean brains had a behavioral node that was analogous to the Human pineal gland. (VOY: "Repentance")

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