A physio-emotive disorder was a medical condition that affects the somatic nervous system; the patient's symptoms included being impatient and quick to anger.

While functioning as the ECH in 2376, The Doctor, attempting to stall for time, told the Hierarchy Overlooker who was threatening the USS Voyager, that he appeared to have had a physio-emotive disorder, based on his temperament. The Doctor would go on to suggest that he might want to see a doctor, after asking in the Overlooker had any idea what those conditions do to his vascular pressure. (VOY: "Tinker Tenor Doctor Spy")

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