The Orion sector was a region of space. The star Orion and the planets Orion, Orion I, and Orion III were located in this sector. (TNG: "Conspiracy", okudagram)

This sector was only mentioned in writing.
On the map of Sector 001, one of the locations depicted was, Orion Sector Tactical Command. Starfleet operations in the Orion sector were coordinated from this starbase.