An organelle was any part of a cell with a specific function.
In 2374, after Seven of Nine's separation from the Borg, her Human immune system restarted and rejected anything Borg, including her Borg organelles. (VOY: "The Gift")
Later that year, Seven's dormant Borg nanoprobes reactivated and caused a high concentration of Borg organelles to appear in her bone marrow and lymphatic tissue. (VOY: "The Raven")
Mitochondria were a type of organelle. In a botany lesson for Naomi Wildman in 2375, The Doctor pointed out such an organelle and described its form as "like a little bitty potato." (VOY: "Once Upon a Time")
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