The Onias sector was a region of space in the Beta Quadrant, near Romulan territory. The Alpha Onias system was located in this sector.

In the 2360s, there were rumors about a secret Romulan base in this sector. In 2367, the USS Enterprise conducted a security survey of this sector. (TNG: "Future Imperfect")

Alpha Onias, the primary of the Alpha Onias system, was located in the Beta Quadrant on a star chart seen in the Star Trek: Discovery episode "Magic to Make the Sanest Man Go Mad".

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