An occupational hazard was a side effect of having a particular occupation.
In 2152, upon hearing Ambassador V'Lar express her wish to be treated as an ordinary individual for once, rather than feeling as though she were making a state visit, Jonathan Archer queried if the unwelcome deference was an occupational hazard. (ENT: "Fallen Hero")
Freighter blight was an occupational hazard of working on a Malon export vessel. Only three out of ten core laborers survived a typical mission. Malon accepted the risk due to the high payout for only two months work. In 2375, Fesek seemed to accept his eventual deterioration, repeating the mantra that it was an occupational hazard. (VOY: "Juggernaut")