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Norepinephrine (abbreviated norep) or noradrenaline is a hormone and neurotransmitter in the humanoid central nervous system. As a stress hormone, it affects the part of the brain that controls alertness as well as the fight-or-flight response. Along with epinephrine or adrenaline, it increases heart rate and blood pressure, thus increasing blood flow to muscles in addition to triggering the release of glucose from the body's energy stores. (TNG: "Skin of Evil", "Who Watches The Watchers")

In 2372, The Doctor found elevated levels of norepinephrine in Lon Suder, which suggested increased aggressive tendencies. However, he also noted that Suder's levels were not significantly different from any of the other former Maquis crew. (VOY: "Meld")

The Clown, a manifestation of fear in Viorsa's virtual reality stasis system, metaphorically chopped his victims' heads off by raising the amount of norepinephrine in their bodies to such extreme levels that they suffered massive heart attacks and died. (VOY: "The Thaw")

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