Neural nodes are pressure points in a humanoid body, the stimulation of which is a Vulcan practice called neuro-pressure. (ENT: "The Xindi", et al.) There are many neural nodes in the soles of the feet, at least in a Human body. (ENT: "Extinction") There are also several neural nodes on a Vulcan's back. (ENT: "The Xindi")

In 2153, T'Pol explained to Charles Tucker III that the neural nodes which needed to be stimulated, in order to help her sleep, were difficult to reach, as they were on her back. During Tucker's first ever neuro-pressure session, he managed to stimulate those hard-to-reach neural nodes. (ENT: "The Xindi") As Tucker later told Malcolm Reed, T'Pol was also teaching Tucker how to stimulate his own neural nodes, in order to help him sleep too. (ENT: "Anomaly") As remembered by Sim, T'Pol and Tucker worked on stimulating the neural nodes on each other's feet. (ENT: "Similitude")