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Nanoprobe graphic

A Ferengi graphic of nanoprobes

Nanoprobe schematic, 2153

A nanoprobe schematic

Nanoprobes in action

Nanoprobes assimilating blood cells

Borg nanoprobes repair cells


Nanoprobes were microscopic robotic devices used by the Borg for the primary purpose of assimilation. Injected into a target's bloodstream via assimilation tubules, the nanoprobes immediately began to take over the host cells' functions. Nanoprobes could also be modified for a variety of medical and technical tasks. (VOY: "Scorpion")

Each drone's nanoprobes have a unique encoding sequence. (VOY: "One")

Seven of Nine's body contained 3.6 million nanoprobes as of 2377. (VOY: "Inside Man")

When Borg drones attempted to assimilate Doctor Phlox of Enterprise NX-01, his Denobulan immune system was able to fight off the nanoprobes long enough for him to discover that they were vulnerable to omicron particles. However the scale of the radiation dose required to destroy every nanoprobe in his body in one blast before they could adapt to the treatment meant that this method could not be used against the assimilation process on a larger scale, Phlox only surviving due to the immune system that allowed him to resist them for so long. (ENT: "Regeneration")

In 2371, Beverly Crusher removed a nanoprobe from Geordi La Forge after he had been captured and tortured by Tolian Soran. (Star Trek Generations)

The novelization of the film explains the nanoprobe that Crusher removed was a Borg nanoprobe put in La Forge's heart by Soran to stop it at will.

In 2374, The Doctor was able to modify nanoprobes as an offensive weapon against Species 8472. He reprogrammed them to mimic the alien cells' electrochemical signatures, so that they could evade detection by Species 8472's immune system while continuing to assimilate. These nanoprobes could be delivered inside a photon torpedo or along a phaser beam. (VOY: "Scorpion", "Scorpion, Part II", "Prey")

Nanoprobes could also be modified to attack specific cells which contained a virus or some other disease and so help the patient recover. In 2375, Seven of Nine encoded some of her nanoprobes to assimilate the synthehol molecules in Kadi Ambassador Tomin's bloodstream, allowing him to recover from his intoxication in time to return to his people. (VOY: "Someone to Watch Over Me")

Since bio-neural circuitry is organic in nature, nanoprobes could also be used to influence or disable this type of circuitry. (VOY: "Warhead")

In 2377, Borg nanoprobes were worth six bars of latinum each on the open market. In that year, Ferengi marauders attempted to obtain Seven of Nine's nanoprobes by perpetrating an elaborate scheme, in which a reprogrammed hologram of Reginald Barclay would bring the USS Voyager to them through a geodesic fold, with the effect of killing the entire crew due to the radiation they were exposed to while traversing the fold. (VOY: "Inside Man")

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