Multi-infarct dementia was a type of dementia suffered by Humans.

Multi-infarct dementia was among the symptoms of transporter psychosis, a condition that results from the break down of neurochemical molecules during transport that affected motor functions, autonomic systems and the brain's higher reasoning centers. (TNG: "Realm of Fear")

Commander William T. Riker of the USS Enterprise -D portrayed a character with this disorder for Dr. Beverly Crusher's play "Frame of Mind." While on a mission to Tilonus IV, Riker was captured and made to believe he was actually suffering from this disorder, presumably in order to extract information; while under this influence, Riker experienced alternating and competing "realities" where he was either on board the Enterprise performing the play, or living out plot details of the play in a mental institution on Tilonus IV. During one of these incidents where he believed he was acting out the play, he acted out against who he believed was one of the aliens responsible for his condition; after of which, Data commented that his "improvised performance" created a highly accurate portrayal of the disorder. (TNG: "Frame of Mind")

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