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Cats are traditionally known to chase mice. As of 2370, Data's cat Spot had never encountered a mouse or any other form of rodent, which once left Data at a loss to explain what the cat was dreaming about. (TNG: "Phantasms")
The cat-and-mouse relationship eventually lent itself to the phrase "cat-and-mouse game", when one individual or group persistently chases another. (TOS: "Friday's Child", "The Squire of Gothos"; TAS: "Once Upon a Planet"; VOY: "Equinox, Part II")