Motion sickness is a physiological condition in which a disagreement exists between visually perceived movement and the vestibular system's sense of movement.

In 2152, Hoshi Sato declined to try a device in Enterprise NX-01's gymnasium, giving motion sickness as an excuse. (ENT: "Vanishing Point")

Later that year, Doctor Phlox mentioned to Malcolm Reed that he'd treated several crewmen for motion sickness during the neutronic storm. (ENT: "The Catwalk")

In 2375, The Doctor claimed he was suffering from "a little motion sickness" while traveling at transwarp in the Delta Flyer. He needed to adjust his matrix to accommodate for the extreme velocity. (VOY: "Dark Frontier")

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