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James T. Kirk, having traveled to 1930s Earth, explained Spock's appearance to a police officer by claiming it was the result of plastic surgery performed by a missionary in China after a mechanical rice picker accident. (TOS: "The City on the Edge of Forever")
In 2366, Q, having been rendered Human by the Q Continuum, sarcastically stated that he would perform missionary work instead of continuing his previous terrorizing ways. Data claimed such work would be "noble". (TNG: "Deja Q")