Melina II was the inhabited second planet in its star system. The Gray Municipality was located here, as well as two medical facilities, the Wiemer Medical Facility and the Taylor Hospital
This planet was one of eleven visited by a group of Ullian telepathic historians in the 2360s, who collected a library of memories from the inhabitants. There were no reported cases of unexplained comas following their visit. However, several apparent cases of Iresine syndrome were later discovered to have been caused by telepathic memory invasions through the Ullian Jev. (TNG: "Violations")
In 2371, the location of Melina II was labeled in the star chart Data and Picard were studying in stellar cartography aboard the USS Enterprise-D. (Star Trek Generations, display graphic)
According to StarTrek.com and the script for the episode, the pronunciation for Melina was "meh-LEEN-uh".