Mazar was the homeworld of the Mazarites, whose government was known as the Mazarite High Council. Mazar was one of the planets involved in the Interspecies Medical Exchange in the 2150s. (ENT: "Affliction")

Enterprise NX-01 visited the planet in 2152 to bring the Vulcan ambassador V'Lar home. V'Lar had been attempting to expose corrupt Mazarite officials there. (ENT: "Fallen Hero")

According to Star Trek: Star Charts (p. 60) and Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), there was a star system named Mazar ("Star Trek: Star Charts") or Manzar ("Stellar Cartography: The Starfleet Reference Library"), in which this planet might possibly have been located, in the Beta Quadrant. The system's primary was a K-class star. The Enterprise visited this system on February 9, 2152. By the late 24th century, the Federation had established the Manzar colony on a planet in this system. This colony was listed as a member planet of the Federation in 2378.
According to, Mazar was located in the Alpha Quadrant.