The Manual on Penal Colony procedures was a Starfleet guidebook about procedures involving penal colonies.

In 2266, Captain James T. Kirk advised Lieutenant Berkley to refamiliarize himself with the manual, moments after Berkley unconfidently beamed cargo including infra-sensory drugs from the USS Enterprise to Tantalus colony in return for some research material destined for Central Bureau of Penology on Earth. Berkley agreed to consult the manual immediately, though Kirk suggested he first take the time to secure the research material. (TOS: "Dagger of the Mind")

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